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Healing is Voltage

Cancer’s On/Off Switches: Polarity

By Jerry Tennant, MD, MD(H), PScD

Summary: Theodor Heinrich Boveri reasoned in 1902 that a cancerous tumor begins with a single cell in which the makeup of its chromosomes becomes scrambled, causing the cells to divide uncontrollably. This was the predominant theory until 2014 when Thomas Seyfried et al proved that genetic changes were secondary in cancer. Thus physicians have been searching for the cause of cancer since the time of Hippocrates in 400 BC. Perhaps the cause of cancer has been elusive because the evidence supports the theory that the cause is a reversal of polarity instead of biochemical. The On switch for cancer is an accumulation of electron stealers in an acupuncture circuit; the Off switch for cancer is removing the causes of low voltage and inserting enough electrons to reverse the polarity back to normal.

Footnotes:

Chapter 1: Overview

  1. Angiogenesis as Inducted by Trophoblast and Cancer Cells; Christofferson RH; Diss Abstr Int [C] (1989) 50(1):35 1989;ISSN: 0419-4217
  2. Maximov, A: Carnegie Contrib. Embryol. 16:47, 1924.
  3. http://stemcells.nih.gov/info/basics/basics4.asp
  4. Rosalind Franklin: The Dark Lady of DNA
  5. From Heresy To Dogma In Accounts Of Opposition To Howard Temin’s DNA Provirus Hypothesis; Marcum JA; Hist Philos Life Sci (2002) 24(2):165-92 ISSN: 03919714
  6. Prospective randomized trial of docetaxel versus best supportive care in patients with non-small-cell lung cancer previously treated with platinum-based chemotherapy: Shepherd FA, Dancey J, Ramlau R, Mattson K, Gralla R, O’Rourke M, Levitan N, Gressot L, Vincent M, Burkes R, Coughlin S, Kim Y, Berille J; J Clin Oncol (2000 May) 18(10):2095-103 ISSN: 0732-182X
  7. High-dose vitamin C versus placebo in the treatment of patients with advanced cancer who have had no prior chemotherapy. A randomized double-blind comparison: Moertel CG, Fleming TR, Creagan ET, ubin J, O’Connell MJ, Ames MM; N Engl J Med (1985 Jan 17) 312(3):137-41; ISSN: 0028-4793
  8. Cancer (1998 Sep 15) 83(6):1142-52 ISSN: 0008-543X
  9. Multicenter phase II study of capecitabine in paclitaxel-refractory metastatic breast cancer: Blum JL, Jones SE, Buzdar AU, LoRusso PM, Kuter I, Vogel C, Osterwalder B, Burger HU, Brown CS, Griffin T; J Clin Oncol (1999 Feb) 17(2):485-93; ISSN: 0732-183X
  10. Phase II and pharmacologic study of docetaxel as initial chemotherapy for metastatic breast cancer: Hudis CA, Seidman AD, Crown JP, Balmaceda C, Freilich R, Gilewski TA, Hakes TB, Currie V, Lebwohl DE, Baselga J, Raptis G, Gollub M, Robles M, Bruno R, Norton L: J Clin Oncol (1996 Jan) 14(1):58-65 : 0732-183X
  11. Clin Oncol (R Coll Radiol). 2004 Dec; 16(8):549-60. The contribution of cytotoxic chemotherapy to 5-year survival in adult malignancies.; Morgan G1, Ward R, Barton M.

Chapter 3: Medical Studies

  1. “Is Relationship Between Serum Cholesterol and Risk of Premature Death From Coronary Heart Disease Continuous and Graded? Finding in 356,222 Primary Screenees of the Multiple Risk Factor Intervention Trail (MRFIT).” Stamler J., Wentworth, D., and Neaton, J.D., JAMA (1986 Nov 28), 256(20): 28238 ISSN: 0098-7484
  2. https://en.wikipedia.org/wiki/Eric_Topol
  3. The U.S. Health Care System: Christopher J.L., Murray, M.D., D.Phil., and Julio Frenk, M.D., Ph.D., M.P.H.; N Engl J Med 2010; 362:98-99 January 1, 2010 DOI: 10.1056/NEJMp0910064
  4. Data are from the Australian Bureau of Statistics, the US National Center for Health Statistics, and the World Health Organization.

Chapter 4: Acupuncture Muscle Batteries

  1. http://taoism.about.com/od/qigongchinesemedicine/a/acupuncture.htm
  2. https://en.wikipedia.org/wiki/Acupunture
  3. https://en.wikipedia.org/wiki/Meridian_(chinese_medicine)
  4. https://en.wikipedia.org/wiki/San_Jiao

Chapter 5: The Acupuncture System

  1. The Anatomical Record, Volume 269, Issue 6, 2002, pp. 257-265. Relationship of acupuncture points and meridians to connective tissue planes. Helene M. Langevin, Jason A. Yandow.
  2. https://en.wikipedia.org/wiki/Chakra

Chapter 7: Causes of Low Voltage

  1. Seneff et al. Theoretical Biology and Medical Modelling (2015) 12:9DOI 10.1186/s12976-015-0006-1; A novel hypothesis for atherosclerosis as acholesterol sulfate deficiency syndrome; Stephanie Seneff1*, Robert M. Davidson2, Ann Lauritzen3, Anthony Samsel4 and Glyn Wainwright

Chapter 9: Nutrition

  1. AMA References: Taddei et al. Hypertension 2001, Egashira et al. Circulation 1993, Celermajer et al JACC 1994, Gerhard et al. Hypertension 1996.
  2. Br J Pharmacol. 2014 Oct 8. doi: 10.11 11/ bph.12960. [Epub ahead of print] Cardio Nitric Oxide Signaling in Metabolic Sydrome. Pechánová O1, Varga Z, Cebová M, Giricz A, Pacher P, Ferdinandy P.

Chapter 10: Proof of Concept

  1. Int J Dermatol. 2015 Jan 20. doi: 10.11 11/ijd.12385 Transcutaneous electrical nerve stimulation for chronic post-herpetic neuralgia Ing MR1, Hellreich PD, Johnson DW, Chen JJ.

Chapter 12: History of Cancer

  1. https://en.wikipedia.org/wiki/Edwin_Smith_Payprus
  2. https://en.wikipedia.org/wiki/Four_temperaments
  3. Curr Stem Cell Res The. 2008 Jan; 3(1):53-4.; Stem cells and blastemal cells.; Tsonis PA1
  4. https://en.wikipedia.org/wiki/Rudolf_Virchow
  5. Lusitani Z. Praxis Medical Admiranda. Lugduni: J. Hugvetan; 1649. Tulp N. Observations Medicae. Amstelredami: Elzevirium; 1652.
  6. Hajdu SI, Thun, MJ, Hannan, LM, Jermal A (June 2011). “A note from history: landmarks in history of cancer, part 2.” Cancer 117 (12): 2811-20.
  7. https://en.wikipedia.org/wiki/katsusabur%C5%8D_Yamagiwa
  8. https://en.wikipedia.org/wiki/Francis_Peyton_Rous
  9. https://en.wikipedia.org/wiki/Howard_Martin_Temin
  10. https://en.wikipedia.org/wiki/WIlliam_Stewart_Halsted
  11. http://irapilgrim.mcn.org/toc21.html
  12. 2013;119:1402-11. Survival After Lumpectomy and Mastectomy for Early Stage Invasive Breast Cancer: The Effect of Age and Hormone Receptor Status; E. Shelley Hwang, MD, MPH; Daphne Y. Lichtensztajn, MS; Scarlett Lin Gomez, PhD; Barbara Fowble, MD; and Christina A. Clarke, PhD
  13. https://en.wikipedia.org/wiki/Marie_Curie
  14. https://en.wikipedia.org/wiki/Emil_Grubbe
  15. https://en.wikipedia.org/wiki/Theodor_Boveri
  16. https://en.wikipedia.org/wiki/Louis_S._Goodman
  17. Temporary remissions in acute leukemia in children produced by folic acid antagonist, 4-aminopteroyl-glutamic acid.; Farber S, Diamond, LK. N Engl J med. 1948 Jun 3;238(23):787-93.
  18. https://en.wikipedia.org/wiki/Aminopterin
  19. https://en.wikipedia.org/wiki/Mary_Lasker
  20. https://en.wikipedia.org/wiki/Dana%E2%80%93Farber_Cancer_Institute
  21. [Oncogenes illustration by unknown illustrator. This image was released by the National Cancer Institute, an agency of the National Institutes of Health, with the ID 2351. This tag dose not indicate the copyright status of the attached work. A normal copyright tag is still required. See Commons: Licensing for more information. English | Français | +/-. Licensed under Public Domain via Wikimedia Commons – http://commons.wikimedia.org/wiki/FIle:Oncogenes_illustration.jpg#/media/File:Oncogenes_illustration.jpg]
  22. https://en.wikipedia.org/wiki/Oncogene
  23. 2014 Mar; 35(3):515-27. doi: 10.1093/carcin/bgt480. Epub 2013 Dec 16.; Cancer as a metabolic disease: implications for novel therapeutics.; Seyfriend TN1, Flores RE, Poff AM, D’Agostino DP.

Chapter 13: Early Diagnosis Testing for Cancer

  1. J Clin Oncol. 2000 May;18(10):2095-103.; Prospective randomized trial for docetaxel versus best supportive care patents with non-small-cell lung cancer previously treated with platinum-based chemotherapy.; Shepherd FA1, Dancey J, Ramlau R, Mattson K, Gralla R, O’Rourke M, Levitan N, Gressot L, Vincent M, Burkes R, Coughlin S, Kim Y, Berille J.
  2. Is screening for breast Cancer with mammography justifiable?; Dr Peter C Gøtzsche, MD, Ole Olsen, MSc; The Lancet: Volume 355, No. 9198, p129-134, 8 January 2000.
  3. Swedish two-country trial: impact of mammographic screening on breast cancer mortality during 3 decades.; Tabár L1, Vitak B, Chen TH, Yen AM, Cohen A, Tot T, Chiu SY, Chen SL, Fann JC, Rosell J, Fohlin H, Smith RA, Duffy SW.; Radiology. 2011 Sep;260(3):658-63. doi: 10.1148/radiol.11110469. Epub 2011 Jun 28.
  4. Abolishing Mammography Screening Programs? A view from the Swiss Medical Board: Nikola Biller-Andorno, M.D., Ph. D., and Peter Jüni, M.D.; N Engl J Med 2014; 370:1965-1967 May 22, 2014 DOI: 10.1056/NEJMp1401875
  5. Breast Cancer Screening: Toward Informed Decisions: Joann G. Elmore, MD, MPH1; Barnett S. Kramer, MD, MPH2; JAMA. 2014;311(13):1298-1299. doi: 10.1001/jama.2014.2494.
  6. Diagnostic Concordance Among Pathologists Interpreting Breast Biopsy Specimens: Joann G. Elmore, MD, MPH1; Gary M. Longton, MS2; Patricia A. Carney, PhD3; Berta M. Geller, EdD4; Tracy Onega, PhD5; Anna N. A. Tosteson, ScD5,6; Heidi D. Nelson, MD, MPH7,8,9; Margaret S. Pepe, PhD2; Kimbery H. Allison, MD10; Stuart J. Schnitt, MD11,12; Frances P. O’Malley, MB13,14; Donald L. Weaver, MD15; JAMA. 2015;313(11):1122-1132. doi:10.1001/jama.2015.1405.
  7. National expenditure for false-positive mammograms and breast cancer over-diagnoses estimated at $4 billion a year: Health Aff (Millwood). 2015 Apr 1;34(4):576-83. doi:10.1377/hlthaff.2014.1087.
  8. Evaluation of digital infrared thermal imaging as an adjunctive screening method for breast carcinoma: a pilot study.; Rassiwala M1, Mathur P2, Mathur R3, Farid K3, Shukla S3, Gupta PK4, Jain B4.; Int J Surg. 2014 Dec;12(12):1439-43. doi: 10.1016/j. ijsu.2014.10.010. Epub 2014 Nov 7.
  9. Randomized prostate cancer screening trial: 20 year follow-up. Sandblom G, Varenhorst E, Rosell J, Lofman O, Carlsson P.; CLINTEC, Karolinska Institute, 141 86 Stockholm, Sweden. BMJ. 2011 Mar 31;342:d1539. doi: 10.1136/bmj.d1539.
  10. Mortality Results from a Randomized Prostate-Cancer Screening Trial: Gerald L. Andriole, M.D., E. David Crawford, M.D., Robert L. Grubb, III, M.D., Saundra S. Buys, M.D., David Chia, Ph.D., Timothy R. Church, Ph.D., Mona N. Fouad, M.D., Edward P. Gelmann, M.D., Paul A. Kvale, M.D., Douglas J. Reding, M.D., Joel L. Weissfeld, M.D., Lance A. Yokochi, M.D., Barbara O’Brien, M.P.H., Jonathan D. Clapp, B.S., Joshua M. Rathmell, M.S., Thomas L. Riley, B.S., Richard B. Hayes, Ph.D., Barnett S. Kramer, M.D., Grant Izmirlian, Ph.D., Anthony B. Miller, M.B., Paul F. Pinsky, Ph.D., Philip C. Prorok, Ph. D., John K. Gohagan, Ph.D., and Christin D. Berg, M.D. for the PLCO Project Team. N Engl J Med 2009; 360:1310-1319 March 26, 2009; DOI: 10.1056/NEJMoa0810696
  11. Screening and Prostate-Cancer Mortality in a Randomized European Study. Fritz H. Schröder, M.D., Jonas Hugosson, M.D., Monique J. Roobol, Ph.D., Teuvo L.J., Tammela, M.D., Stefano Ciatto, M.D., Vera Nelen, M.D., Maciej Kwiatkowski, M.D., Marcos Lujan, M.D., Hans Lilja, M.D., Marco Zappa, Ph.D., Louis J. Denis, M.D., Franz Recker, M.D., Antonio Berenguer, M.D., Liisa Määttänen, Ph.D., Chris H. Bangma, M.D., Gunnar Aus, M.D., Arnauld Villers, M.D., Xavier Rebillard, M.D., Theodorus van der Kwast, M.D., Bert G. Blijenberg, Ph.D., Sue M. Moss, Ph.D., Harry J. de Koning, M.D., Anssi Auvinen, M.D., for the ERSPC Investigators; The New England Journal of Medicine; Volume 360:1320-1328; March 26, 2009; Number 13.
  12. NY Times, March 9, 2010 THE GREAT PROSTATE MISTAKE Richard Albin, PhD
  13. https://en.wikipedia.org/wiki/Human_chorionic_gonadotropin
  14. https://ori.hhs.gov/education/products/ucla/chapter 3/page01/htm

Chapter 14: Cancer’s Off Switch

  1. The Enzyme Treatment of Cancer by John Beard, PhD, published 1911.
  2. https://en.wikipedia.org/wiki/Exlampsia
  3. Semin Repro Endocrinol. 1999;17(3):275-90.; Embryo implantation and tumor metastasis: common pathways of invasion and angiogenesis.; Murray MJ1, Lessey BA.
  4. Hum Reprod Update. 2007 Mar-Apr;13(2):121-41. Epub 2006 Oct 26.: Molecular circuits shared by placental and cancer cells, and their implications in the proliferative, invasive and migratory capacities of trophoblasts.; Ferretti C1, Bruni L, Dangles-Marie V, Pecking AP, Bellet D.
  5. NSG, or NOD scid gamma (NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ), is a strain of inbred laboratory mice, among the most immunodeficient described to date. [1] NSG mice lack mature T cells, B cells, and natural killer (NK) cells. [2] NSG mice are also deficient in multiple cytokine signaling pathways, and they have many defects in innate immunity. The compound immunodeficiencies in NSG mice permit the engraftment of a wide range of primary human cells, and enable sophisticated modeling of many areas of human biology and disease.
  6. https://en.wikipedia.org/wiki/Cancer_stem_cell
  7. Nature, Chen et al, 2012
  8. The Biology of Cancer stem Cells; Annual Review of Cell and Developmental Biology; Vol. 23:675-699 (Volume publication date November 2007)
  9. Shively FL: Multiple Proteolytic Enzyme Therapy of Cancer. Dayton: Johnson-Watson, 1969
  10. Reprinted from Pharmacology Biochemistry & Behavior, v. 21, Suppl., 1, by A. Keith Brewer, Ph.D., “The High pH Therapy for Cancer, Tests on Mice and Humans,” pp. 1-5, Copyright 1984, with permission from Elsevier Science

Chapter 15: Cancer’s On Switch

  1. https://en.wikipedia.org/wiki/Mutation
  2. Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer; June 26, 2012 by Thomas Seyfried.
  3. 2014 Mar;35(3):515-27. doi: 10.1093/carcin/bgt480. Epub 2013 Dec 16.; Cancer as a metabolic disease: implications for novel therapeutics.; Seyfried TN1, Flores RE, Poff AM, D’Agostino DP.
  4. The glucose ketone index calculator: a simple tool to monitor therapeutic efficacy for metabolic management of brain cancer; Meidenbauer JJI, Mukherjee P1, Seyfriend TN
  5. Zilberter Y, Zilberter T, Bregestovski P (September 2010). “Neuronal activity in vitro and the in vivo reality: the role of energy homeostasis”. Trends Pharmacol. Sci. 31 (9): 2=394-401. doi:10.1016/j. tips. 2010.06.005. PMID 20633934. Jump up ^ Wyss MT, Jolivet R, Buck A, Magistretti PJ, Weber B (May 2011). “In vivo evidence for lactate as a neuronal energy source”. J. Neurosci. 31(20): 7477-8.
  6. Gladden LB (July 2004). “Lactate metabolism: a new paradigm for the third millennium”. J Physiol. (Lond.) 558 (Pt 1): 5-30. doi: 10.1113/jphysiol.2003.058701. PMC 1664920. PMID 15131240. Jump up ^ Pellerin L, Bouzier-Sore Ak, Aubert A et al. (September 2007). “Activity-dependent regulation of energy metabolism by astrocytes: an update”. Glia 55 (12): 1251-62. doi: 10.1002/glia.20528. PMID 17659524.
  7. https://en.wikipedia.org/wiki/Lactic_acid
  8. 2010 Feb 5; 140(3):327-37. doi: 10.1; Acid extrusion from human spermatozoa is mediated by flagellar voltage-gated proton channel. Lishko PV1, Botchkina IL, Fedorenko A, Kirichok Y.
  9. http://www.ncbi.nlm.nioh.gov/pubmed/20144758
  10. 2011 Mar 17;471(7338):387-91. doi: 10.1038/nature09767. Progesterone activates the principal Ca2+ channel of human sperm Lishko PV1, Botchikina IL, Kirichok Y.
  11. https://en.wikipedia.org/wiki/Macrophage
  12. https://en.wikipedia.org/wiki/Gc-MAF
  13. The GcMAF Book; Timothy J. Smith, M.D.
  14. Biochem Biophys Res Commun. 1989 Sep 29;163(3): 1498-504. Molecular Cloning of a Full-Length Cdna For Human  Alpha-N-Acetylgalactosamin-idase (Alpha-Galactosidase B).; Tsuji S1, Yamauchi T, Hiraiwa M, Isobe T, Okuyama T, Sakimura K, Takahashi Y, Nishizawa M, Uda Y, Miyatake T.

Chapter 16: Dental Connection

  1. Compend Contin Educ Dent. 2000 Jan;21(1):15-8, 21-4, 26 passim; quiz 30.; Secondary caries and restoration replacement: an unresolved problem. Fontana M, González-Cabezas C.; Oral Health research Institute, Indiana University School of Dentistry, Indianapolis, Indiana, USA.
  2. Roggenkamp, Clyde, PhD, Dentinal Fluid Transport, Loma Linda, Calif., Loma Linda Univ. Press, 2004.
  3. http://www.copalite.com/Dentinal%20Tubular%20Flow%20and%20Effective%20Caries%20Treatment-%20revised.htm
  4. http://articles.mercola.com/sites/articles/archive/2010/11/16/why-you-should-avoid-root-canals-like-the-plague.aspx
  5. https://en.wikipedia.org/wiki/Hydrogen_sulfide

Chapter 17: Hypothyroidism

  1. Psychiatry Res. 1983 Sep;10(1):1-9.; Reverse T-3 levels in affective disorders.; Kjeillman BF, Ljunggren JG, Beck-Friis J, Wetterberg L.
  2. Psychiatry Research; Volume 6, Issue 3, June 1982, Pages 271-276; High reverse T-3 levels in manic and unipolar depressed women; Markku Linnoila, a, Bror-Axel Lambergb, William Z. Potterc, Philip W. Goldd, Frederick K. Goodwine
  3. Hypothyroidism: The Unsuspected IllnessHardcover; January 1, 1976; by Broda Barnes
  4. 2007 Jul; 17(7):609-12.; Effects of 12 months treatment with L-seleomethionine on serum anti-TPO Levels in Patients with Hashimoto’s thyroiditis.; Mazokopakis EE1, Papadakis JA, Papadomanolaki MG, Batistakis AG, Giannakopoulos TG, Protopapadakis EE, Ganotakis ES.
  5. Mahmood Bhat GH – “Effect of fluoride ions on the thyroid glands of guinea pigs” JK Practitioner International 3(2): 94-6 (1996)
  6. Understanding Local Control of Thyroid Hormones: (Deiodinases Function and Activity); National Academy of Hypothyroidism—http://nahpothyroidism.org
  7. http://www.labcorp.com/wps/portal/!u/p/c1/04_SB8K8xLLM9MSSzPy8xBz9CP0os_hAC-zO_QCM_IwMLXyM3AyNjMycDU2dXQwN3M6B-8JG55AwMCuv088nNT9SP1o8zjQ11Ngg-09LY0N_N2DjQw8g439TfyM_MzMLAz0Q_QjnYCKIvEqKsiNKDFUDVQEAOrk-dE!/dl2/d1/L01JWmltbUEhL3dQRUJGUUFoTlFBaER-hQUVBWEtHL11JNXlsdyEhLzdfVUU0UzFJOTMwT0dTMjBJUzNPNE4yTjY2ODAvdmlldlRlc3Q!/?testId=408027
  8. January 2003 American Academy of Clinical Endocrinology press release
  9. National Academy of Clinical Biochemistry: Laboratory Support for the Diagnosis and Monitoring of Thyroid Disease: Published Guidelines (US, 2002)
  10. Psychiatry Res. 1983 Sep; 10(1):1-9.; Reverse T-3 levels in affective disorders.; Kjellman BF, Ljunggren JG, Beck-Friis J, Wetterberg L.
  11. Biosci Rep. 2002 Feb;22(1):17-32. Thyroid hormones and mitochondria. Goglia F, Silvestri E, Lanni A. Source: Facoltà de Scienze, Università degli Studi del Sannio, Benevento, Italy. goglia@unisannio.it

Chapter 18: Vaccines

  1. Merck Manual 8th Basic Immunization Schedule – Optional schedule No. 1. 1950. pg. 1462
  2. Jonas Salk, Science, April 4, 1977.
  3. Epidemiology of Polio in the U.S. One Decade after the Last Reported Case of Indigenous Wild Virus Associated Disease (Stebel, et al., CDC, February 1992, pp. 568-579)
  4. Shedding of Virulent Poliovirus Revertants during Immunization with Oral Poliovirus Vaccine after Prior Immunizaiton with Inactivated Polio Vaccine, Journal of Infectious Diseases 1993; 168.
  5. Aust J Exp Biol Med Sci 1963 Aug; 41:SUPPL467-89
  6. N Engl J Med. 1987 Mar 26;316(13):771-4. Measles outbreak in fully immunized secondary-school population. Gustafson TL, Lievens AW, Brunell PA, Moellenberg RG, Buttery CM, Sehulster LM.
  7. Am J Public Health. 1999 Jan; 89(1):79-81. Persistence of susceptibility to measles in France despite routine immunization: a cohort analysis.; Chauvin P1, Valleron AJ.
  8. Urban measles in the vaccine era: A clinical, epidemiologic, and serologic study 1. M.D. James D. Cherry*, M.D. Ralph D. Feigin**, M.D. Louis A. Lobes Jr.***, M.D. Daniel R. Hinthorn***, M.D. Penelope G. Shackelford, B.S. Richard H. Shirley, M.D. Robert D. Lins, Ph.D. Sung C. Choi
  9. http://www.cdc.gov/mmwr/preview/mmwrhtml/ss610al.htm
  10. http://www.lifesteps.com/gm/Atoz/ency/tetanus/jsp
  11. From CDC website
  12. http://www.pharmexec.com/brand-year-0
  13. 2009 Aug 19;302(7):781-6.; Marketing HPV vaccine: implications for adolescent health and medical professionalism.; Rothman SM, Rothman DJ
  14. http://www.businesswire.com/portal/site/home/permalink/?ndmViewId=news_view&newsId=20090209005358&newsLang=en
  15. Li Y, Carroll DS, Gardner SN, Walsh MC, Vitalis EA, Damon IK (2007). “On the origin of smallpox correlating variola phylogenics with historical smallpox records”. Proc Natl Acad Sci USA 104 (40): 15787—15792.Bibcode:2007PNAS..10415787L. doi: 10.1073/pnas.0609268104. PMC 2000395. PMID 17901212.
  16. http://articles.mercola.com/sites/articles/archive/2001/05/05/vaccination-smallpox.aspx.
  17. http://vaers.hhs.gov/index
  18. Influenza Body Count: The math behind estimating seasonal flu deaths. By Jordan Ellenberg; Posted Thursday, May 14, 2009. At 12:20 PM ET; http://www/slate.com/id/2218367/
  19. Kitching A, Rocke A, Balasegaram S, Heathcock R, Maguire H. Oseltamivir adherence and side effects among children in three London schools affected by influenza A(H1N1)v, May 2009 – an internet-based cross-sectional survey. Euro Surveill. 2009; 14(30):pii=19287. Available online: Date of submission: 20 July 2009 wurosurveillance.org/ViewArticle.aspx?ArticvleId=19287
  20. Eurosurveillance, Volume 14, Issue 30, 30 July 2009; Oseltamivir Adherence And Side Effects Among Children In Three London Schools Affected By Influenza A(H1n1)V, May 2009 – An Internet-Based Cross-Sectional Survey; A Kitching ()1,2, A Roche3, S Balasegaram4, R Heathcock5, H Maguire3
  21. Antibodies to squalene in Gulf War syndrome.; Asa PB, Cao Y, Garry RF; Exp Mol Pathol (2000 Feb) 68(1):55-64 ISSN: 0014-4800
  22. Effectiveness of Influenza Vaccine in the Community-Dwelling Elderly; Kristin L. Nichol, M.D., M.P.H., M.B.A., James D. Nordin, M.D.., M.P.H., David B. Nelson, Ph.D., John P. Mullooly, Ph.D., and Eelko Hak, Ph.D.; N Engl J Med 2007; 357:1373-1381 October 4, 2007 DOI: 10.1056/NEJMoa070844
  23. texmed.org/Template.aspx?id=24579#sthash.04Hzg7eh.dpuf
  24. Increase in Incidence of Insulin-Dependent Diabetes Mellitus among Children in Finland; J Tuomilehto*, E Virtala*, M Karvonen*, R Lounamaa*, J Pitkāniemi*, A Peunanen†, E Tuomilehto-Wolf*, L Toivanen* And The Dime Study Group
  25. Blaylock Reports Volume 8 Number 2
  26. Ethnic Differences in the Incidence of Childhood IDDM in Israel (1965-1993): Marked increase since 1985, especially in Yemenite Jews; Igor Shamis, MD, Orit Gordon, MA, Yael Albag, RN, George Goldsand, MSCand Zvi Laron, MD
  27. Diabetes Care. 1997 Apr;20(4):504-8. Ethnic differences in the incidence of childhood IDDM in Israel (1965-1993). Marked increase since 1985, especially in Yemenite Jews.;Shamis I1, Gordon O, Albag Y, Goldsand G, Laron Z.
  28. Association between type 1 diabetes and Haemophilus influenza type b vaccination: birth cohort study; BMJ 1999; 318 doi: http://dx.doi.org/10.1136/bmj.318.7192.1169(Published 1 May 1999); Cite this as: BMJ 1999;318:1169
  29. Aluminum vaccine adjuvants: are they safe?; Cur Med Chem. 2011;18(17):2630-7.; Tomljenovic L, Shaw CA.; Aluminum Vaccine Adjuvants: Are They Safe?
  30. http://www.autisable.com/757367903/the-amish-don%E2%80%99t-get-autism-and-they-aren%E2%80%99t-vaccinated/
  31. “Deadly Immunity” by Robert F. Kennedy Jr. For the complete article, see http://www.whale.to/vaccine/kenndy.html
  32. http://www.nvic.org/vaccine-laws/state-vaccine-requirements.aspx
  33. http://publichealth.gwu.edu/departments/healthpolicy/influenza/MODEL%20LAW%20REPORT.pdf

Chapter 19: GMO Foods

  1. http://en.wikipedia.org/wiki/Glyphosate
  2. http://articles.mercola.com/sites/articles/archive/2013/04/30/monsanto-gmo-corn.aspx
  3. Hilbeck et al. Environmental Sciences Europe (2015) 27:4 DOI 10.1186/s12302-014-0034-1; No scientific consensus on GMO safety. Angelika Hilbeck 1,2, Rosa Binimelis1,3, Nicolas Defarge1,4,5, Ricarda Steinbrecher1,6, András Székács1,7, Fern Wickson1,3, Michael Antoniou8, Philip L Bereano9, Ethel Ann Clark10, Michael Hansen11, Eva Novotny12, Jack Heinemann13, Hartmut Meyer1, Vandana Shiva14 and Brain Wynne15
  4. Environmental Sciences Europe: Republished study: long-term toxicity of a Roundup herbicide and a Roundup-tolerant genetically modified maize Gilles-Eric Séralini1, Emilie Clair1, Robin Mesnage1, Steeve Gress1, Nicolas Defarge1, Manuela Malatesta2, Didier Hennequin3 and Joël Spiroux de Vendômois1
  5. Environ Health Perspect. 2014 Oct;122(10):1103-9. doi: 10.1289/ehp.1307044. Epub 2014 Jan 23.; Neurodevelopmental disorders and prenatal residential proximity to agricultural pesticides: the CHARGE study. Shelton JF1, Geraghty EM, Tancredi DJ, Delwiche LD, Schmidt RJ, Ritz B. Hansen RL, Hertz-Picciotto I.
  6. http://ee.congress.gov/bill/113th-congress/house-bill/4432/all-info
  7. Copyright: © 2015 Samsel A. This is an open-access article distributed under the terms of the Creative Common Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. How to cite this article: Samsel A, Seneff S, Glyphosate, pathways to modern diseases III: Manganese, neurological diseases, and associated pathologies. Surg neurol Int 24-Mar-2015;6:45

Glyphosate, pathways to modern diseases III: Manganese, Neurological diseases, and associated pathologies Anthony Samsel, Stephanie Seneff

Research Scientist and Consultant, Deerfield, NG 03037, 1Spoken Language Systems Group, Computer Science and Artificial Intelligence Laboratory, MIT, Cambridge MA 02139, USA

E-mail: Anthony Samsel: anthonysamsel@acoustictracks.net, Stephani Seneff: seneff@csail.mit.edu Corresponding author. Received: September 22, 2014; accepted: January 21, 2015; published: March 24, 2015

Chapter 22: Electron Donors

  1. Antiproliferative and proapoptotic effect of ascorbyl stearate in human pancreatic cancer cells: association with decreased expression of insulin-like growth factor 1 receptor.: Naidu KA, Karl RC, Naidu KA, Coppola D; Dig Dis Sci (2003 Jan) 48(1):230-71
  2. Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition: Khaw KT, Bingham S, Welch A, Luben R, Wareham N, Oakes S, Day N; Lancet (2001 Mar 3) 357(9257):657-63
  3. Epidemiologic evidence regarding vitamin C and cancer: Block G: Am J Clin Nutr (1991 Dec) 54(6 Suppl):1310S-
  4. Vitamin C and cancer prevention: the epidemiologic evidence: Block G; Am J Clin Nutr (1991 Jan) 53(1 Suppl):270S-282S SSN: 0002-9165
  5. http://www.aquiziam.com/ancient-mysteries/ancient-electricity/
  6. http://www.rife.de/scoon_website.html
  7. http://www.rife.de/scoon_website.html
  8. JAMA June 12, 1954 Fishbein, M
  9. http://www.mdanderson.org/departments/CIMER/display.ctmid=73835819-07FC-11D5-810C0050B603A14&method=displayFull&pn=6EB86A59E BD9=11D4-810100508B603A14
  10. Written by Rene Caisse, was published posthumously by the Bracebridge Examiner, January, 1979
  11. http://essiacingo.org/caisse.html
  12. http://en.wikipedia.org/wiki/Max_Gerson
  13. Free Radical Biology and Medicine Volume 27, Issues 1-2, July 1999, Pages 220-226
  14. 1999;9(2-4):365-70.; CoQ10: could it have a role in cancer management?; Hodges S1, Hertz N, Lockwood K, Lister R.; University of Sheffield, UK.

Chapter 23: Oxygen

  1. https://en.wikipedia.org/wiki/Otto_Heinrich_Warburg
  2. How Tumor Cells Work Overtime to Restore Vascular Health; Stephanie Seneff, Weston Price Kim JW, Dang CV. Cancer’s molecular sweet tooth and the Warburg effect. Cancer Res 2006, 66(18):8927-8930.
  3. Seneff et al. Theoretical Biology and Medical Modeling (2015) 12:9; A novel hypothesis for atherosclerosis as a cholesterol sulfate deficiency syndrome; Stephanie Seneff, Robert M. Davidson, Ann Lauritzen, Anthony Samsel and Glyn Wainwright
  4. https://en.wikipedia.org/wiki/Otto_Heinrich_Warbug
  5. http://www.huffingtonpost.com/2013/07/16/sugar-toxic-health-effects-sucrose-fructose_n_3599864.html
  6. Takahashia I, Noguchia N, Nata K, Yamada S, Kaneiwa T, et al. Important role of heparin sulfate in postnatal islet growth and insulin secretion. Biochemical and Biophysical Research Communications 2009 May 22, 383(1):113-118.
  7. Zilberter, Yuri; Bregestovski, Piotr; Mukhtarov, Marat; Ivanov, Anton (2011). “Lactate Effectively Covers Energy Demands during Neuronal Network Activity in Neonatal Hippocampal Slices”

Chapter 24: Summary

  1. https://en.wikipedia.org/wiki/Lysosome
  2. http://www.texastribune.org/2011/06/17/2011-veto-watch-perry-kills-24-bills-in-one-day-/
  3. http://www.cdc.gov/ncbddd/autims/data.html
  4. How Tumor Cells Work Overtime to Restore Vascular Health; Stephanie Seneff; westonaprice.org/modern-disease/cancer-to-the-rescue/