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Neurotoxic Effects of Mercury Exposure in Dental Personnel

Bjørklund, G, Hilt, B, Dadar, M, Lindh, U, Aaseth, J. Neurotoxic effects of mercury exposure in dental personnel. Basic Clin Pharmacol Toxicol. 2019; 124: 568– 574. https://doi.org/10.1111/bcpt.13199

Numerous studies have reported neurobehavioural effects in dental personnel occupationally exposed to chronic low levels of mercury (Hg). Hg exposure from dental work may also induce various chronic conditions such as elevation of amyloid protein expression, deterioration of microtubules, and increase or inhibition of transmitter release at motor nerve terminal endings. Therefore, clinical studies of Hg toxicity in dentistry may provide new knowledge about disturbed metal homeostasis in neurodegenerative diseases such as Alzheimer's disease, multiple sclerosis, and mood disorders.

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